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Featured Research Associate:
Mark Stenglein
In the Harris lab, Mark’s doctoral research has focused on a family of human proteins named the APOBEC3s. These proteins have the ability to deaminate (i.e. to chemically modify) DNA. Read more about Mark Stenglein...
Advances in DNA sequencing technology have made it possible to identify the many genes within an organism’s genome. Two current challenges are to understand how these genes work together to dictate how an organism grows and develops and how to make changes in genomes for medical and commercial purposes. Meeting these challenges requires sophisticated tools to manipulate genes. The mission of the Center for Genome Engineering is to develop and disseminate the tools that enable efficient, responsible genome engineering.
At the heart of the CGE’s genome engineering technology are transposable elements – segments of DNA capable of changing their chromosomal position or moving from one DNA molecule to another. Transposable elements constitute a large portion of DNA in many organisms. They naturally shape the genetic code by causing mutations, rearrangements and sequence duplications. At the Center for Genome Engineering, scientists are harnessing these naturally occurring genome engineers to enable precise changes to the genetic code.
We are excited by the progress of the Center since its establishment in 1999 and by the many discoveries of Center scientists that enable new approaches to genome engineering. The Center is poised for the next decade of discovery and is ready to implement its technologies to solve real world problems.
In the News
Yuen-Yi Tseng and Vitaliy Baranyuk receive travel awards to present their work in the Bagchi Lab. Read more...
David Largaespada, Timothy Starr, and Vincent Keng are featured in the news for discovering 32 new genes linked to cancer using the Sleeping Beauty method. Read more news...
Reuben Harris receives $100K grant for research 'Mortalizing HIV - A Novel Method to Help Eradicate AIDS'. Article featured on KSTP news, read here...
Dan Voytas featured on UMN news for research published in Nature. Full article here...